Historic Downtown Mixed-Use Building — Retail, Office & Medical Space in Opportunity Zone

421–427 2nd Avenue SW is a ±20,000 SF historic mixed-use cornerstone positioned at a signalized downtown intersection directly across from the Cullman County Courthouse. The property includes three ground-floor commercial suites—one improved for medical office use with existing exam rooms and waiting areas—and approximately 13 dedicated professional offices across the first and second floors. Multiple break rooms, reception areas, and support spaces create a functional layout for medical, professional, and service-oriented users. A vacant 1-bedroom apartment offers optional rental income or conversion flexibility.

The building combines classic brick architecture with selective interior updates, maintaining Main Street character while supporting modern tenant needs. Lower-level areas include ±8,900 SF of basement and mezzanine storage suitable for records, inventory, or potential future expansion. Currently operated as a multi-tenant professional office center, the asset generates stable income with clear value-add potential through lease-up, suite modernization, or retail reactivation along 2nd Avenue.

Surrounded by restaurants, boutiques, financial institutions, and civic buildings, the property benefits from consistent foot traffic and strong daytime population generated by the courthouse and adjacent government complex. B-3 General Business zoning supports a wide range of commercial uses, from medical and professional offices to boutique retail and creative concepts. Located within a federally designated Opportunity Zone, the property also offers investors access to tax-advantaged investment strategies.

With character, functionality, and meaningful upside, 421–427 2nd Avenue SW stands as one of downtown Cullman’s most compelling mixed-use offerings—an income-producing cornerstone with multiple paths for future value creation.